Radioactive sodium chromate for the study of survival of red blood cells. I. The effect of radioactive sodium chromate on red cells.
نویسندگان
چکیده
منابع مشابه
Effect of Ascorbic Acid in Vivo on Labeling of Red Cells by Radioactive Sodium Chromate.
S INCE THE INITIAL work of Gray and Sterling,”2 the determination of red cell mass with radioactive sodium chromate has undergone several modifications. Read’ developed the technic of adding ascorbic acid in vitro to the blood-sodium chromate mixture to reduce chromate to trivalent chromium and prevent further uptake by red cells. The inhibition of chromium uptake by ascorbic acid supported the...
متن کاملLife Span of Reticulocytes in Paroxysmal Nocturnal Hemoglobinuria.
P REVIOUS OBSERVATIONS have demonstrated the shortened life span of the red cell in patients with paroxysmal nocturnal hemoglohinuria ( PNH ).1.2 Studies of the survival of homologous PNH red cells by the Ashby technic and of autologous PNH cells labeled with radioactive sodium chromate have demonstrated a short and biphasic red cell survival curve in the patient and normal recipient. This life...
متن کاملImpairment of red cell viability by exposure to "excess" acid--citrate dextrose.
By KLAUS MAYER, ALLYN B. LEY AND JOSEPH D’AMARO ARLY IN THE DEVELOPMENT of the Cr’1 method for the measure.4 ment of red blood cell survival, it was demonstrated by Ebaugh et al.’ that excess concentrations of chromium were toxic and impaired the viability of red blood cells. Accordingly, in order to achieve an adequate level of radioactivity when tagged blood was injected into the experimental...
متن کاملThe red cell chromium elution rate in patients with some hematologic diseases.
By M iiTIN J. CLINE AND NATHANIEL I. Bi ur. G RAY AND STERLING demonstrated that red cells can bind radioactive sodium chromate ( Na2 Cr51O4 ) in vitro rapidly and without apparent damage to the exposed cells.’ The chromium-51 labeling technic was rapidly adopted for the measurement of total red cell volume and red cell life span.26 As an erythrocyte label it possesses the advantage that it is ...
متن کاملStudies on Chromated Erythrocytes. Effect of Sodium Chromate on Erythrocyte Glutathione Reductase.
The marked affinity of erythrocytes for hexavalent chromate anion was reported in 1950 by Gray and Sterling (1). Since then, erythrocytes labeled with radioactive sodium chromate have been used extensively for the determination of erythrocyte survival in vivo (1-5) and the determination of blood volume (4-6). The anionic hexavalent form of chromium is bound firmly to erythrocytes, is not reutil...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of laboratory and clinical medicine
دوره 42 3 شماره
صفحات -
تاریخ انتشار 1953